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  • Writer's pictureEscuela de alopecia

New Non-Hormonal Treatment for Your Alopecia: CXCL12

In this post, I want to share with you a recent discovery that could change the paradigm in the treatment of androgenetic alopecia and other autoimmune forms of hair loss. Let's delve into a new non-hormonal treatment for your alopecia: CXCL12.


The Cable, the Bulb, and the Switch

Over the years, I've lost hope in significant breakthroughs to combat baldness. However, there has been recent discussion about a finding that could be a game-changer in alopecia treatment. How does this process work?


In simple terms, imagine your hair as a cable connected to a bulb and controlled by a switch. Male sex hormones, especially testosterone, act as the cable, the hormone receptor is the switch, and the command to go bald is the bulb. The intensity of the light (baldness) depends on the power of the cable (type of hormone). This is where treatments come in: some block hormone production, while others reduce its intensity.


Paradigm Shift: CXCL12

Let's talk about a recent discovery called CXCL12. This protein, found in the hair follicle's dermal papilla, is involved in various biological processes, including autoimmune hair loss. Studies in mice show that blocking CXCL12 can make hair regrow, even under the influence of male hormones.


Potential Future Treatment: Antibody Mesotherapy

The application of antibodies through mesotherapy could be the future treatment for alopecia. These antibodies locally block the action of CXCL12 without affecting other vital body functions. Although it is a promising approach, research is ongoing to fully understand its effectiveness and safety.


Final Considerations

In summary, we are in an exciting time for hair care. Combining existing treatments with innovative approaches like modulating CXCL12 could offer more effective and personalized solutions to combat baldness. Don't forget to take care of your hair and follow medical recommendations.




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