QR678 New treatment for androgenetic alopecia
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This is an automatic translation of my post in Spanish, it is possible that there are grammatical errors.
Today we have to talk about a product, a product that comes from India, specifically the QR678. I am going to tell you what it is, how it works, what components it has and the studies that support it and my opinion at the end.
Apparently the name QR678 according to the authors comes from the morse code QR (quick response in English) and 678 from the morse code "no answer". In other words, the authors have called their product a rapid response product to something that has no answer, which is androgenic alopecia, a bit bombastic ...
It is a product that has to be applied in a traditional way, that is, by pricking the scalp. It is applied as if it were a mesotherapy or plasma with platelets. According to its authors, what it contains are several proteins and peptides, which have a certain action similar to some growth factors. Are:
VEGF (human oligogeptide-11) FGF (human oligopeptide-3) IGF (human oligopeptide-2) Copper tripeptide-1 KGF (human polypeptide-3) Appper triden de-1 KGF (human polypeptide-3) Thymosin B4
Therefore they include growth factors, fibroblast or vascular growth stimulating factors, etc., and also add vitamins, proteins and other trace elements. And what these authors have done is a series of studies that have been practically all published in the same scientific journal in women, men and in people who have had hair loss after chemotherapy. The treatment is applied for several weeks infiltrated into the scalp.
Chen one reads these studies, the truth is that I am not going to fool you, they are a bit wicked. I don't want to get into this because it is not the objective of my channel, but it is to give you my opinion, which in the end is what you want from me.
I say that the studies are open to criticism for several reasons: first, the methodology. The photographs I have seen are very bad, they are poor quality photos. Sometimes they seem at the patient's home or a poorly focused hospital background. Sometimes they are with a mobile, not with a suitable camera. They are not standardized, in short. On the other hand, the hairstyles of the patients are different and above all they are not standardized photographs. I also see that there is a very high conflict of interest since the creators of this product are the same ones who have done the study. This is unusual. Normally, when a study is done correctly, the company that promotes it hires a team that will design the test and execute it. This study must have internal and external validity, that is; that the results are reproducible in other parts of the world. And in this aspect I have very reasonable doubts that they can be reproducible as those referenced in QR 678. In addition, it is not clear if these patients are taking another medication or not, because the methodology is a bit confusing and in the end we have to believe it. that they tell us. And it is curious because what these authors have done has been to publish very similar studies in the same scientific journal, separated by a month. Fundamentally the studies have been published in the year 2020. Apparently the results of the studies are good, especially that they are, let's say, products that can help reduce hair loss. But we have said it many times, the important thing is to recover hair. It is much more important that you increase the density and thickness and not so much the fall. Hair that often falls out then reappears and the issue of hair loss is not something we really care about in the long run. It can temporarily cause a loss of volume but it is something that plays a trick on the patient's appreciation, but fortunately, and speaking objectively, the important thing is to see that there are more hairs and greater thickness.
The authors try to compare them to something that is currently established and made many parts, which is platelet-rich plasma. According to the authors, it is better than platelet-rich plasma. You already know that platelet-rich plasma is not always interesting. Just for the effluvium but saving this I do not think it has much interest to thicken the hair.
Also in the studies the authors compare the use of these products with men who use finasteride and obviously it improves much more, which I believe perfectly. In the end what works is what works. The authors also comment that it has patents and it is true, it has a patent in India and the United States. Although they mention that it is FDA approved and it is not. Keep it in mind.
Thus, the summary about QR 678 is that it is a cosmetic product, not a drug: I am not very interested in it. I can say that I am probably not interested in my patients. I am a very skeptical person by nature and after seeing the studies I do not see that it has any interest in the current context. What it could have is simply that it will probably be considered as something new, especially in more aesthetic clinics.
If that may be something that appears in some clinics that do not like to propose powerful treatments and is more a little cosmetic: "I prick this and we continue to tangle the skein, we do not end the problem but we continue ..." I think that if you are looking for something For it to be an effective alternative, you must go to the highly effective treatments that we currently have and that are very effective. You can see them on my channel, in the ranking of treatments for men and women. Currently there are drugs that are super effective especially in men to recover hair and currently the appearance of QR 678 is not something that is going to make it different at all.
Excuse me for being frank but I am very direct so we have already settled the matter of this product.